Drug-resistance Epilepsy

Epilepsy is affecting nearly 50 million people worldwide. Several medications are available. However, approximately 1/3 of the patients are drug-resistant and continue to experience seizures. Furthermore, the side effects make the availability of other treatments necessary. Almost half of the patients with epilepsy are looking for other medical therapies to ameliorate the seizure burden and improve quality of life (Sadeghifar & Baute Penry, 2019). The ketogenic diet, a high fat, low protein, low carbohydrate diet has been used as a method for almost 100 years and is accepted as an effective protocol (Williams & Cervenka, 2017). The diet leads to a more than 50% seizure reduction in 36-85% of patients and positively affects cognition (van Berkel, IJff, & Verkuyl, 2018).

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